Saving Limbs and Lives Everyday®
Best Reported Long-Term Survival for Bone Cancer

The intraarterial chemotherapy protocol developed in cooperation with Colorado State University's Animal Cancer Center is utilized at The Denver Clinic for treatment of osteosarcoma and malignant fibroushistiosarcoma of the extremity in children and adults. Patient outcomes following treatment using the I-A protocol by the Denver Clinic physicians have resulted in the best 10-year survival for bone cancer in kids and adults compared to any other center in the world. 

 

The Denver Clinic physicians have published these outcomes in peer reviewed journals. For more information please feel free to contact The Denver Clinic at 1-800-262-5462.

 

The articles are available by clicking the links below.

Superior Survival in Treatment of Primary Nonmetastatic Pediatric Osteosarcoma of the Extremity: Wilkins RM, Cullen JC, Odom LF, Jamroz BA, et al; Annals of Surgical Oncology, 2003, 10(5):498-507

 

Hugate et al. Intraarterial chemotherapy for extremity osteosarcoma and MFH in adults. Clin Orthop Relat Res. 2008 Jun;466(6):1292-301 PMID: 18437502

 

 Cullen et al. The value of serial arteriography in osteosarcoma: delivery of chemotherapy, determination of therapy duration, and prediction of necrosis. J Vasc Interv Radiol. 2005 Aug; 16(8): 1107-19

 

Wilkins et al. Improved survival in primary nonmetastatic pediatric osteosarcoma of the extremity. Clin Orthop Relat Res. 2005 Sep; 438: 128-36. PMID: 16131881

 

 

 

Intraarterial Chemotherapy for Extremity Osteosarcoma and MFH in Adults: Hugate RR, Wilkins RM, Kelly CM, Hinshaw I, et al: Clinical Orthopedics and Related Research, 2008, 466:1292-1301

Hugate and Josh ElliotDr. Ron Hugate was interviewed by Josh Elliot and Matt Lauer on The Today Show on October 17, 2014 as part of the NFL stories series, hosted by NBC.  Dr. Hugate discussed how his participation in football when growing up has influenced his work as an orthopedic oncologist. He explained how important a team of experts has been in developing The Denver Clinic's bone cancer treatment protocol which has the achieved the best reported long-term survival for kids and adults diagnosed with bone cancer compared to all other cancer centers.  He credits the expertise of the medical specialists, nurses and other healthcare providers in the success of the protocol used at The Denver Clinic. To watch the Today Show interview click here>>>



 

meet the team

Brooke Pengel, MD

thumb_B.Pengel.wDr. Brooke Pengel is a member of the Denver Clinic for Extremities at Risk hip preservation team. She is a pediatric orthopedic surgeon and expert in sports medicine and serves as medical director of the Rocky Mountain Youth Sport Medicine Institute at Rocky Mountain Hospital for Children. She has published widely, been quoted in many publications, presented and lectured on the subject of sports injuries in children and adolescents. She has served as team physician for the University of Denver Women's Soccer Team and University of Colorado Women's Volleyball Team

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